Intracellular transactivation of HIV can account for the decelerating decay of virus load during drug therapy

Abstract Basic virus dynamics models have been essential in understanding quantitative issues of HIV replication. However, several parts of the viral life cycle remain elusive. One of the most critical steps is the start of viral transcription, which is governed by the regulatory protein trans‐activ...

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Bibliographic Details
Main Authors: Christian L Althaus, Rob J De Boer
Format: Article
Language:English
Published: Springer Nature 2010-02-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2010.4