CD18 controls the development and activation of monocyte-to-macrophage axis during chronic schistosomiasis

CD18 controls the development and activation of monocyte-to-macrophage axis during chronic schistosomiasis

Schistosomiasis is a neglected tropical disease caused by worms of the genus Schistosoma spp. The progression of disease results in intense tissue fibrosis and high mortality rate. After egg deposition by adult worms, the inflammatory response is characterized by the robust activation of type 2 immu...

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Bibliographic Details
Main Authors: Camila O. S. Souza, Jefferson Elias-Oliveira, Marcella R. Pastore, Caroline Fontanari, Vanessa F. Rodrigues, Vanderlei Rodriguez, Luiz G. Gardinassi, Lúcia H. Faccioli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
β2 integrin
monocytes
proliferation
alternatively activated macrophages
schistosomiasis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.929552/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.929552/full

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