Atypical Teratoid Rhabdoid Tumours Are Susceptible to Panobinostat-Mediated Differentiation Therapy

Atypical Teratoid Rhabdoid Tumours Are Susceptible to Panobinostat-Mediated Differentiation Therapy

Atypical teratoid rhabdoid tumour (ATRT) is a rare but highly aggressive undifferentiated solid tumour arising in the central nervous system and predominantly affecting infants and young children. ATRT is exclusively characterized by the inactivation of <i>SMARCB1</i>, a member of the SW...

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Bibliographic Details
Main Authors: Wai C. Chong, W. Samantha N. Jayasekara, Vijesh G. Vaghjiani, Sarah Parackal, Claire Sun, Dean Popovski, Elizabeth M. Algar, Ron Firestein, Paul J. Wood, Sara Khan, Annie Huang, David M. Ashley, Peter Downie, Jason E. Cain
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
atypical teratoid rhabdoid tumour
panobinostat
HDACi
differentiation
Online Access:https://www.mdpi.com/2072-6694/13/20/5145

Internet

https://www.mdpi.com/2072-6694/13/20/5145

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