Interleukin-1β triggers matrix metalloprotease-3 expression through p65/RelA activation in melanoma cells.

Interleukin-1β triggers matrix metalloprotease-3 expression through p65/RelA activation in melanoma cells.

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Melanoma shows highly aggressive behavior (i.e., local invasion and metastasis). Matrix metalloprotease-3 (MMP-3), a zinc-dependent endopeptidase, degrades several extracellular substrates and contributes to local invasion by creating a microenvironment suitable for tumor development. Here, we repor...

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Bibliographic Details
Main Authors: Junichi Nunomura, Rei Nakano, Atsuto Naruke, Yoko Suwabe, Masumi Nakano, Naoya Yachiku, Manami Kuji, Mana Sugimura, Shinichi Namba, Taku Kitanaka, Nanako Kitanaka, Hiroshi Sugiya, Tomohiro Nakayama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0278220

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https://doi.org/10.1371/journal.pone.0278220

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