Constructing Lipoparticles Capable of Endothelial Cell-Derived Exosome-Mediated Delivery of Anti-miR-33a-5p to Cultured Macrophages

Constructing Lipoparticles Capable of Endothelial Cell-Derived Exosome-Mediated Delivery of Anti-miR-33a-5p to Cultured Macrophages

Atherosclerosis is driven by intimal arterial macrophages accumulating cholesterol. Atherosclerosis also predominantly occurs in areas consisting of proinflammatory arterial endothelial cells. At time of writing, there are no available clinical treatments that precisely remove excess cholesterol fro...

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Bibliographic Details
Main Authors: Jing Echesabal-Chen, Kun Huang, Lucia Vojtech, Olanrewaju Oladosu, Ikechukwu Esobi, Rakesh Sachdeva, Naren Vyavahare, Hanjoong Jo, Alexis Stamatikos
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Current Issues in Molecular Biology
Subjects:
antagomiR
HDL
intima
microRNA
nanoparticle
reverse cholesterol transport
Online Access:https://www.mdpi.com/1467-3045/45/7/355

Internet

https://www.mdpi.com/1467-3045/45/7/355

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