Design of experiments for fine-mapping quantitative trait loci in livestock populations

Design of experiments for fine-mapping quantitative trait loci in livestock populations

Abstract Background Single nucleotide polymorphisms (SNPs) which capture a significant impact on a trait can be identified with genome-wide association studies. High linkage disequilibrium (LD) among SNPs makes it difficult to identify causative variants correctly. Thus, often target regions instead...

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Bibliographic Details
Main Authors: Dörte Wittenburg, Sarah Bonk, Michael Doschoris, Henry Reyer
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Genetics
Subjects:
Single nucleotide polymorphism
Statistical power
Target region
SNP-BLUP
Linkage disequilibrium
Online Access:http://link.springer.com/article/10.1186/s12863-020-00871-1

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http://link.springer.com/article/10.1186/s12863-020-00871-1

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