Reduced HGF/MET Signaling May Contribute to the Synaptic Pathology in an Alzheimer's Disease Mouse Model
Alzheimer's disease (AD) is a neurodegenerative disorder strongly associates with aging. While amyloid plagues and neurofibrillary tangles are pathological hallmarks of AD, recent evidence suggests synaptic dysfunction and physical loss may be the key mechanisms that determine the clinical synd...
Main Authors: | Jing Wei, Xiaokuang Ma, Antoine Nehme, Yuehua Cui, Le Zhang, Shenfeng Qiu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-07-01
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Series: | Frontiers in Aging Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2022.954266/full |
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