rSeqDiff: detecting differential isoform expression from RNA-Seq data using hierarchical likelihood ratio test.

High-throughput sequencing of transcriptomes (RNA-Seq) has recently become a powerful tool for the study of gene expression. We present rSeqDiff, an efficient algorithm for the detection of differential expression and differential splicing of genes from RNA-Seq experiments across multiple conditions...

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Bibliographic Details
Main Authors: Yang Shi, Hui Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3832546?pdf=render