Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis

Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis

Intravascular erythrocyte destruction, accompanied by the release of pro-oxidative and pro-inflammatory components hemoglobin and heme, is a common event in the pathogenesis of numerous diseases with heterogeneous etiology and clinical features. A frequent adverse effect related to massive hemolysis...

Full description

Bibliographic Details
Main Authors: Nicolas S. Merle, Anne Grunenwald, Marie-Lucile Figueres, Sophie Chauvet, Marie Daugan, Samantha Knockaert, Tania Robe-Rybkine, Remi Noe, Olivia May, Marie Frimat, Nathan Brinkman, Thomas Gentinetta, Sylvia Miescher, Pascal Houillier, Veronique Legros, Florence Gonnet, Olivier P. Blanc-Brude, Marion Rabant, Regis Daniel, Jordan D. Dimitrov, Lubka T. Roumenina
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
hemolysis
heme
kidney injury
endothelial activation
inflammation
hemopexin
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00179/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00179/full

Similar Items