Hypoxia-sensitive cells trigger NK cell activation via the KLF4-ASH1L-ICAM-1 axis, contributing to impairment in the rat epididymis

Hypoxia-sensitive cells trigger NK cell activation via the KLF4-ASH1L-ICAM-1 axis, contributing to impairment in the rat epididymis

Summary: Male infertility is a global health problem especially prevalent in high-altitude regions. The epididymis is essential for sperm maturation, but the influence of environmental cues on its reshaping remains poorly understood. Here, we use single-cell transcriptomics to track the cellular pro...

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Bibliographic Details
Main Authors: Jitao Zeng, Weiwu Gao, Ying Tang, Ying Wang, Xiaona Liu, Jun Yin, Xingxing Su, Mengjie Zhang, Enchuan Kang, Yi Tian, Bing Ni, Wei He
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723014547

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http://www.sciencedirect.com/science/article/pii/S2211124723014547

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