Vascular response patterns to targeted therapies in murine breast cancer models with divergent degrees of malignancy

Vascular response patterns to targeted therapies in murine breast cancer models with divergent degrees of malignancy

Abstract Background Response assessment of targeted cancer therapies is becoming increasingly challenging, as it is not adequately assessable with conventional morphological and volumetric analyses of tumor lesions. The tumor microenvironment is particularly constituted by tumor vasculature which is...

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Bibliographic Details
Main Authors: Emily Hoffmann, Mirjam Gerwing, Tobias Krähling, Uwe Hansen, Katharina Kronenberg, Max Masthoff, Christiane Geyer, Carsten Höltke, Lydia Wachsmuth, Regina Schinner, Verena Hoerr, Walter Heindel, Uwe Karst, Michel Eisenblätter, Bastian Maus, Anne Helfen, Cornelius Faber, Moritz Wildgruber
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Breast Cancer Research
Subjects:
Tumor vasculature
Magnetic resonance imaging
Targeted therapy
Tumor microenvironment
Immune checkpoint inhibition
Sorafenib
Online Access:https://doi.org/10.1186/s13058-023-01658-9

Internet

https://doi.org/10.1186/s13058-023-01658-9

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