Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells

Background Epithelial-mesenchymal transition (EMT) plays an important role in fibrosis, chronic inflammation, tumor metastasis, etc. Glycyrrhizin, an active component extracted from licorice plant, has been reported to treat a variety of inflammatory reactions through inhibiting high-mobility group...

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Bibliographic Details
Main Authors: Yanni Gui, Jian Sun, Wenjie You, Yuanhui Wei, Han Tian, Shujuan Jiang
Format: Article
Language:English
Published: PeerJ Inc. 2020-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/8514.pdf