Distinct Effects of Contraction Agonists on the Phosphorylation State of Cofilin in Pulmonary Artery Smooth Muscle

We hypothesized that agonist-induced contraction correlates with the phospho-cofilin/cofilin (P-CF/CF) ratio in pulmonary artery (PA) rings and cultured smooth muscle cells (PASMCs). PA rings were used for isometric contractions and along with PASMCs for assay of P-CF/CF by isoelectric focusing and...

Full description

Bibliographic Details
Main Authors: Yan-Ping Dai, Shaner Bongalon, Violeta N. Mutafova-Yambolieva, Ilia A. Yamboliev
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2008/362741