Gram-Negative Bacteria Salmonella typhimurium Boost Leukotriene Synthesis Induced by Chemoattractant fMLP to Stimulate Neutrophil Swarming

Gram-Negative Bacteria Salmonella typhimurium Boost Leukotriene Synthesis Induced by Chemoattractant fMLP to Stimulate Neutrophil Swarming

Leukotriene synthesis in neutrophils is critical for host survival during infection. In particular, leukotriene B4 (LTB4) is a powerful neutrophil chemoattractant that plays a crucial role in neutrophil swarming. In this work, we demonstrated that preincubation of human neutrophils with Salmonella t...

Full description

Bibliographic Details
Main Authors: Ekaterina A. Golenkina, Svetlana I. Galkina, Olga Pletjushkina, Boris Chernyak, Tatjana V. Gaponova, Yulia M. Romanova, Galina F. Sud’ina
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
neutrophil
bacteria Salmonella typhimurium
intracellular calcium
5-lipoxygenase
leukotriene B4
neutrophil swarming
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.814113/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.814113/full

Similar Items