Genomic Characterization and Comparison of Multi-Regional and Pooled Tumor Biopsy Specimens.

A single tumor biopsy specimen is typically used in cancer genome studies. However, it may represent incompletely the underlying mutational and transcriptional profiles of tumor biology. Multi-regional biopsies have the advantage of increased sensitivity for genomic profiling, but they are not cost-...

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Bibliographic Details
Main Authors: Je-Gun Joung, Joon Seol Bae, Sang Cheol Kim, HyunChul Jung, Woong-Yang Park, Sang-Yong Song
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4807092?pdf=render