Pharmacokinetics evaluation of newly formulated beads alginate/gum acacia loaded ketoconazole in rabbit plasma by oral administration

Pharmacokinetics evaluation of newly formulated beads alginate/gum acacia loaded ketoconazole in rabbit plasma by oral administration

Background and purporse: The combination of alginate and gum acacia in previous studies showed good results in inhibiting ketoconazole precipitation due to the supersaturation phenomenon. Ketoconazole-loaded alginate and gum acacia can produce hydrogel beads through cross-linking with Ca2+ using io...

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Bibliographic Details
Main Authors: Viviane Annisa, Teuku Nanda Saifullah Sulaiman, Akhmad Kharis Nugroho, Agung Endro Nugroho
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2023-11-01
Series:ADMET and DMPK
Subjects:
in vivo
bioavailability
hydrogel
polymer
drug
Online Access:https://pub.iapchem.org/ojs/index.php/admet/article/view/2042

Internet

https://pub.iapchem.org/ojs/index.php/admet/article/view/2042

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