Tadalafil significantly reduces ischemia reperfusion injury in skin island flaps

Introduction: Numerous pharmacological agents have been used to enhance the viability of flaps. Ischemia reperfusion (I/R) injury is an unwanted, sometimes devastating complication in reconstructive microsurgery. Tadalafil, a specific inhibitor of phosphodiesterase type 5 is mainly used for erectile...

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Bibliographic Details
Main Authors: Oguz Kayiran, Suat S. Cuzdan, Afsin Uysal, Ugur Kocer
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2013-01-01
Series:Indian Journal of Plastic Surgery
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/0970-0358.113714