The NUCKS1-SKP2-p21/p27 axis controls S phase entry

Entry into S phase of the cell cycle is regulated positively by mitogens and negatively by DNA damage; however, how balance of these signals is achieved is not well known. Here the authors show that the NUCKS1-SKP2- p21/p27 axis integrates this information, where the NUCKS1 transcription factor affe...

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Bibliografische gegevens
Hoofdauteurs: Samuel Hume, Claudia P. Grou, Pauline Lascaux, Vincenzo D’Angiolella, Arnaud J. Legrand, Kristijan Ramadan, Grigory L. Dianov
Formaat: Artikel
Taal:English
Gepubliceerd in: Nature Portfolio 2021-11-01
Reeks:Nature Communications
Online toegang:https://doi.org/10.1038/s41467-021-27124-8