The NUCKS1-SKP2-p21/p27 axis controls S phase entry
Entry into S phase of the cell cycle is regulated positively by mitogens and negatively by DNA damage; however, how balance of these signals is achieved is not well known. Here the authors show that the NUCKS1-SKP2- p21/p27 axis integrates this information, where the NUCKS1 transcription factor affe...
Hoofdauteurs: | , , , , , , |
---|---|
Formaat: | Artikel |
Taal: | English |
Gepubliceerd in: |
Nature Portfolio
2021-11-01
|
Reeks: | Nature Communications |
Online toegang: | https://doi.org/10.1038/s41467-021-27124-8 |