The Effects of Repeated Morphine Treatment on the Endogenous Cannabinoid System in the Ventral Tegmental Area

The therapeutic utility of opioids is diminished by their ability to induce rewarding behaviors that may lead to opioid use disorder. Recently, the endogenous cannabinoid system has emerged as a hot topic in the study of opioid reward but relatively little is known about how repeated opioid exposure...

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Bibliographic Details
Main Authors: Hong Zhang, Austin A. Lipinski, Erika Liktor-Busa, Angela F. Smith, Aubin Moutal, Rajesh Khanna, Paul R. Langlais, Tally M. Largent-Milnes, Todd W. Vanderah
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.632757/full