| Summary: | Water scarcity has been a global challenge for many countries over the past decades, and as a result, reverse osmosis (RO) has emerged as a promising and cost-effective tool for water desalination and wastewater remediation. Currently, RO accounts for >65% of the worldwide desalination capacity; however, membrane fouling is a major issue in RO processes. Fouling reduces the membrane's lifespan and permeability, while also increases the operating pressure and chemical cleaning frequency. Overall, fouling reduces the quality and quantity of desalinated water, and thus hinders the sustainable application of RO membranes by disturbing its efficacy and economic aspects. Fouling arises from various physicochemical interactions between water pollutants and membrane materials leading to foulants' accumulation onto the membrane surfaces and/or inside the membrane pores. The current review illustrates the main types of particulates, organic, inorganic and biological foulants, along with the major factors affecting its formation and development. Moreover, the currently used monitoring methods, characterization techniques and the potential mitigation strategies of membrane fouling are reviewed. Further, the still-faced challenges and the future research on RO membrane fouling are addressed.
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