A new polymorphism biomarker rs629367 associated with increased risk and poor survival of gastric cancer in chinese by up-regulated miRNA-let-7a expression.

A new polymorphism biomarker rs629367 associated with increased risk and poor survival of gastric cancer in chinese by up-regulated miRNA-let-7a expression.

BACKGROUND: Variant in pri-miRNA could affect miRNA expression and mature process or splicing efficiency, thus altering the hereditary susceptibility and prognosis of cancer. We aimed to assess miRNA-let-7 single nucleotide polymorphisms (SNP) associated with the risk and prognosis of gastric cancer...

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Bibliographic Details
Main Authors: Qian Xu, Qiguan Dong, Caiyun He, Wenjing Liu, Liping Sun, Jingwei Liu, Chengzhong Xing, Xiaohang Li, Bengang Wang, Yuan Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3997364?pdf=render

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http://europepmc.org/articles/PMC3997364?pdf=render

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