Serine racemase interaction with N-methyl-D-aspartate receptors antagonist reveals potential alternative target of chronic pain treatment: Molecular docking study

Serine racemase interaction with N-methyl-D-aspartate receptors antagonist reveals potential alternative target of chronic pain treatment: Molecular docking study

Serine racemase (SR) catalyzes L-serine racemization to activate the N-methyl-D-aspartate receptor (NMDAR). NMDAR activation is associated with the progression of acute-to-chronic neuropathic pain. This study aimed to investigate NMDAR antagonist interactions with SR to obtain potential chronic pain...

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Bibliographic Details
Main Authors: Ristiawan Muji Laksono, Handono Kalim, Mohammad Saifur Rohman, Nashi Widodo, Muhammad Ramli Ahmad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
chronic pain
n-methyl-d-aspartate receptor
serine racemase
treatment
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2022;volume=13;issue=3;spage=232;epage=237;aulast=Laksono

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http://www.japtr.org/article.asp?issn=2231-4040;year=2022;volume=13;issue=3;spage=232;epage=237;aulast=Laksono

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