Association Between ABCB1 Polymorphism and Stable Warfarin Dose Requirements in Brazilian Patients

Association Between ABCB1 Polymorphism and Stable Warfarin Dose Requirements in Brazilian Patients

The ideal dose of the oral anticoagulant warfarin varies widely among patients, mainly due to genetic factors. Genetic variations that impact warfarin pharmacokinetics and the vitamin K cycle are plausible candidates for being associated with warfarin dose requirements. Therefore, the aim of this st...

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Bibliographic Details
Main Authors: Letícia C. Tavares, Leiliane R. Marcatto, Renata A. G. Soares, Jose E. Krieger, Alexandre C. Pereira, Paulo C. J. L. Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
warfarin pharmacogenetics
ABCB1
MDR1
CYP4F2
warfarin stable dose
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00542/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00542/full

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