Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex

ClpXP is the main ATP-dependent proteolytic complex in bacteria, is essential for maintaining cellular protein homeostasis and is also critical for bacterial pathogenesis. Here, the authors establish a functional link between ClpXP and trigger actor, a chaperone involved in the early stages of prote...

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Bibliografiska uppgifter
Huvudupphovsmän: Kamran Rizzolo, Angela Yeou Hsiung Yu, Adedeji Ologbenla, Sa-Rang Kim, Haojie Zhu, Koichiro Ishimori, Guillaume Thibault, Elisa Leung, Yi Wen Zhang, Mona Teng, Marta Haniszewski, Noha Miah, Sadhna Phanse, Zoran Minic, Sukyeong Lee, Julio Diaz Caballero, Mohan Babu, Francis T. F. Tsai, Tomohide Saio, Walid A. Houry
Materialtyp: Artikel
Språk:English
Publicerad: Nature Portfolio 2021-01-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/s41467-020-20553-x