Genetic insights: High germline variant rate in an indigenous African cohort with early-onset colorectal cancer

Genetic insights: High germline variant rate in an indigenous African cohort with early-onset colorectal cancer

IntroductionThe increase in incidence of colorectal cancer in young patients of African ancestry coupled with increased aggressiveness has warranted investigation of the heritable nature of these cancers. Only a limited number of published reports of hereditary colorectal cancer in indigenous Africa...

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Bibliographic Details
Main Authors: Safiye Yildiz, Takudzwa N. Musarurwa, Ursula Algar, Ramadhani Chambuso, George Rebello, Paul A. Goldberg, Raj Ramesar
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Oncology
Subjects:
hereditary colorectal cancer (CRC)
next generation sequencing -(NGS)
early-onset colorectal cancer
germline variants
genetic insight
indigenous african cohort
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1253867/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1253867/full

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