Genetic insights: High germline variant rate in an indigenous African cohort with early-onset colorectal cancer
IntroductionThe increase in incidence of colorectal cancer in young patients of African ancestry coupled with increased aggressiveness has warranted investigation of the heritable nature of these cancers. Only a limited number of published reports of hereditary colorectal cancer in indigenous Africa...
Những tác giả chính: | Safiye Yildiz, Takudzwa N. Musarurwa, Ursula Algar, Ramadhani Chambuso, George Rebello, Paul A. Goldberg, Raj Ramesar |
---|---|
Định dạng: | Bài viết |
Ngôn ngữ: | English |
Được phát hành: |
Frontiers Media S.A.
2023-10-01
|
Loạt: | Frontiers in Oncology |
Những chủ đề: | |
Truy cập trực tuyến: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1253867/full |
Những quyển sách tương tự
-
Early-Age-Onset Colorectal Cancer in Canada: Evidence, Issues and Calls to Action
Bằng: Mary A. De Vera, et al.
Được phát hành: (2022-04-01) -
Breaking Down Barriers to Detection and Care in Early-Age-Onset Colorectal Cancer in Canada
Bằng: Michael J. Raphael, et al.
Được phát hành: (2023-10-01) -
Genomic Medicine in the Developing World: Cancer Spectrum, Cumulative Risk and Survival Outcomes for Lynch Syndrome Variant Heterozygotes with Germline Pathogenic Variants in the <i>MLH1</i> and <i>MSH2</i> Genes
Bằng: Lutricia Ndou, et al.
Được phát hành: (2024-12-01) -
Influence of Genetic Polymorphisms on the Age at Cancer Diagnosis in a Homogenous Lynch Syndrome Cohort of Individuals Carrying the <i>MLH1</i>:c.1528C>T South African Founder Variant
Bằng: Lutricia Ndou, et al.
Được phát hành: (2024-09-01) -
Identification of Germline Mutations in Melanoma Patients with Early Onset, Double Primary Tumors, or Family Cancer History by NGS Analysis of 217 Genes
Bằng: Lenka Stolarova, et al.
Được phát hành: (2020-10-01)