Expression of CD39 Identifies Activated Intratumoral CD8+ T Cells in Mismatch Repair Deficient Endometrial Cancer

Expression of CD39 Identifies Activated Intratumoral CD8+ T Cells in Mismatch Repair Deficient Endometrial Cancer

Identification of human cancer-reactive CD8+ T cells is crucial for the stratification of patients for immunotherapy and determination of immune-therapeutic effects. To date, these T cells have been identified mainly based on cell surface expression of programmed cell death protein 1 (PD-1) or co-ex...

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Bibliographic Details
Main Authors: Joyce M. Lubbers, Marta A. Ważyńska, Nienke van Rooij, Arjan Kol, Hagma H. Workel, Annechien Plat, Sterre T. Paijens, Martijn R. Vlaming, Diana C. J. Spierings, Philip H. Elsinga, Edwin Bremer, Hans W. Nijman, Marco de Bruyn
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
CD103
CD39
PD-1
TGF-β
exhaustion
Online Access:https://www.mdpi.com/2072-6694/14/8/1924

Internet

https://www.mdpi.com/2072-6694/14/8/1924

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