Clinical significance of NF2 alteration in grade I meningiomas revisited; prognostic impact integrated with extent of resection, tumour location, and Ki-67 index

Clinical significance of NF2 alteration in grade I meningiomas revisited; prognostic impact integrated with extent of resection, tumour location, and Ki-67 index

Abstract NF2 alteration is the most commonly–found genetic abnormality in meningiomas and is known to initiate events for aggressive-type meningiomas. Whereas the prognosis of meningiomas differs depending on their epigenomic/transcriptomic profile, the effect of NF2 alteration on the prognosis of b...

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Bibliographic Details
Main Authors: Yu Teranishi, Atsushi Okano, Satoru Miyawaki, Kenta Ohara, Daiichiro Ishigami, Hiroki Hongo, Shogo Dofuku, Hirokazu Takami, Jun Mitsui, Masako Ikemura, Daisuke Komura, Hiroto Katoh, Tetsuo Ushiku, Shumpei Ishikawa, Masahiro Shin, Hirofumi Nakatomi, Nobuhito Saito
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Acta Neuropathologica Communications
Subjects:
Meningioma genomics
WHO grade
Tumor location
Tumor prognosis
Precision medicine
Online Access:https://doi.org/10.1186/s40478-022-01377-w

Internet

https://doi.org/10.1186/s40478-022-01377-w

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