Prevalence and Spectrum of Predisposition Genes With Germline Mutations Among Chinese Patients With Bowel Cancer

Prevalence and Spectrum of Predisposition Genes With Germline Mutations Among Chinese Patients With Bowel Cancer

Background: Bowel cancer is the third-most common cancer and the second leading cause of cancer-related death worldwide. Bowel cancer has a substantial hereditary component; however, additional hereditary risk factors involved in bowel cancer pathogenesis have not been systematically defined.Materia...

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Bibliographic Details
Main Authors: Zhengyong Xie, Yongli Ke, Junyong Chen, Zehang Li, Changzheng Wang, Yuhong Chen, Hongliang Ding, Liyang Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Genetics
Subjects:
bowel cancer
germline
somatic
P/LP (pathogenic/likely-pathogenic)
TMB
DDR
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.755629/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.755629/full

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