Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex

Cancer: A search for safer signaling targets More effective treatments for cancer could be developed by targeting signaling pathway regulators that are expressed solely in cancer cells. Disruption to a major signaling pathway known as Wnt, which is involved in processes including cell proliferation,...

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Bibliographic Details
Main Authors: Youn-Sang Jung, Jae-Il Park
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-020-0380-6