P-Glycoprotein 170; Its Clinical Importance and Pathophysiological Role in Cancer

Background: P-glycoprotein 170 is encoded by MDR1 gene and belongs to the ATP-binding cassette transporters (ABC) superfamily. This protein has important roles in cell physiology and its function in cancerous cells may contribute to failure treatment. The molecular structure of P-glycoprotein and it...

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Bibliographic Details
Main Authors: Marjan Abedi, Soheila Rahgozar
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2013-06-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/2484