The Atrophic Effect of 1,25(OH)<sub>2</sub> Vitamin D<sub>3</sub> (Calcitriol) on C2C12 Myotubes Depends on Oxidative Stress

The Atrophic Effect of 1,25(OH)<sub>2</sub> Vitamin D<sub>3</sub> (Calcitriol) on C2C12 Myotubes Depends on Oxidative Stress

Dysfunctional mitochondrial metabolism has been linked to skeletal muscle loss in several physio-pathological states. Although it has been reported that vitamin D (VD) supports cellular redox homeostasis by maintaining normal mitochondrial functions, and VD deficiency often occurs in conditions asso...

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Bibliographic Details
Main Authors: Tommaso Raiteri, Ivan Zaggia, Simone Reano, Andrea Scircoli, Laura Salvadori, Flavia Prodam, Nicoletta Filigheddu
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Antioxidants
Subjects:
skeletal muscle atrophy
aging
cachexia
sarcopenia
vitamin D receptor (VDR)
mitochondrial respiration
Online Access:https://www.mdpi.com/2076-3921/10/12/1980

Internet

https://www.mdpi.com/2076-3921/10/12/1980

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