SGK1-regulated metabolism: key for the survival of cells detached from the extracellular matrix

Cells that lack attachment to the extracellular matrix (ECM) experience metabolic defects that can lead to caspase-independent cell death. Recently, we discovered that serum and glucocorticoid kinase-1 (SGK1) plays a critical role in the regulation of glucose metabolism, the promotion of energy prod...

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Bibliographic Details
Main Authors: Jordan A. Cockfield, Zachary T. Schafer
Format: Article
Language:English
Published: Taylor & Francis Group 2021-09-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2021.1976583