Klotho supplementation reverses renal dysfunction and interstitial fibrosis in remnant kidney.

Introduction: While recent investigations show that klotho exerts reno-protective actions, it has not been fully addressed whether klotho protein supplementation reverses renal damage. Methods: The impacts of subcutaneous klotho supplementation on rats with subtotal nephrectomy were examined. Anima...

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Bibliographic Details
Main Authors: Tsuneo Takenaka, Arif Hasan, Takeshi Marumo, Tsutomu Inoue, Takashi Miyazaki, Hiromichi Suzuki, Yoshifumi Kurosaki, Naohito Ishii, Akira Nishiyama, Matsuhiko Hayashi
Format: Article
Language:English
Published: Karger Publishers 2023-04-01
Series:Kidney & Blood Pressure Research
Online Access:https://www.karger.com/Article/FullText/530469