The Contribution of Genetic Variation and Aberrant Methylation of Aryl Hydrocarbon Receptor Signaling Pathway Genes to Rheumatoid Arthritis

The Contribution of Genetic Variation and Aberrant Methylation of Aryl Hydrocarbon Receptor Signaling Pathway Genes to Rheumatoid Arthritis

The aryl hydrocarbon receptor (AHR) signaling pathway participates in immune regulation of multiple autoimmune diseases, including rheumatoid arthritis (RA). We conducted this study to investigate the association of AHR signaling pathway genes (AHR, ARNT, AHRR) single nucleotide polymorphisms (SNPs)...

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Bibliographic Details
Main Authors: Tian-Ping Zhang, Rui Li, Hong-Miao Li, Nan Xiang, Zhen Tan, Guo-Sheng Wang, Xiao-Mei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
autoimmune disease
aryl hydrocarbon receptor
methylation
single nucleotide polymorphisms
rheumatoid arthritis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.823863/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.823863/full

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