Pathogen-specific epitopes as epidemiological tools for defining the magnitude of Mycobacterium leprae transmission in areas endemic for leprosy.

During recent years, comparative genomic analysis has allowed the identification of Mycobacterium leprae-specific genes with potential application for the diagnosis of leprosy. In a previous study, 58 synthetic peptides derived from these sequences were tested for their ability to induce production...

Full description

Bibliographic Details
Main Authors: Marcia V S B Martins, Marjorie M da S Guimarães, John S Spencer, Mariana A V B Hacker, Luciana S Costa, Fernanda M Carvalho, Annemieke Geluk, Jolien J van der Ploeg-van Schip, Maria A A Pontes, Heitor S Gonçalves, Janvier P de Morais, Tereza J P G Bandeira, Maria C V Pessolani, Patrick J Brennan, Geraldo M B Pereira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3335884?pdf=render