Machine Learning with Alpha Toxin Phenotype to Predict Clinical Outcome in Patients with <i>Staphylococcus aureus</i> Bloodstream Infection

Machine Learning with Alpha Toxin Phenotype to Predict Clinical Outcome in Patients with <i>Staphylococcus aureus</i> Bloodstream Infection

<i>Staphylococcus aureus</i> bloodstream (SAB) infection remains a leading cause of sepsis-related mortality. Yet, current treatment does not account for variable virulence traits that mediate host dysregulated immune response, such as SA α-toxin (Hla)-mediated thrombocytopenia. Here, we...

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Bibliographic Details
Main Authors: Brent Beadell, Surya Nehra, Elizabeth Gusenov, Holly Huse, Annie Wong-Beringer
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Toxins
Subjects:
<i>Staphylococcus aureus</i>
bacteremia
machine learning
platelets
α-toxin
thrombocytopenia
Online Access:https://www.mdpi.com/2072-6651/15/7/417

Internet

https://www.mdpi.com/2072-6651/15/7/417

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