Neural correlates of episodic memory in adults with Down syndrome and Alzheimer’s disease

Neural correlates of episodic memory in adults with Down syndrome and Alzheimer’s disease

Abstract Background Adults with Down syndrome are at an ultra-high risk of developing early-onset Alzheimer’s disease. Episodic memory deficits are one of the earliest signs of the disease, but their association with regional brain atrophy in the population with Down syndrome has not been explored....

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Bibliographic Details
Main Authors: Bessy Benejam, Mateus Rozalem Aranha, Laura Videla, Concepción Padilla, Silvia Valldeneu, Susana Fernández, Miren Altuna, Maria Carmona-Iragui, Isabel Barroeta, Maria Florencia Iulita, Víctor Montal, Jordi Pegueroles, Alexandre Bejanin, Sandra Giménez, Sofía González-Ortiz, Sebastián Videla, David Bartrés-Faz, Daniel Alcolea, Rafael Blesa, Alberto Lleó, Juan Fortea
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Alzheimer’s Research & Therapy
Subjects:
Down syndrome
Alzheimer’s disease
Dementia
Episodic memory
MRI
Cortical thickness
Online Access:https://doi.org/10.1186/s13195-022-01064-x

Internet

https://doi.org/10.1186/s13195-022-01064-x

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