Could Extracellular Vesicles Contribute to Generation or Awakening of “Sleepy” Metastatic Niches?

Pre-metastatic niches provide favorable conditions for tumor cells to disseminate, home to and grow in otherwise unfamiliar and distal microenvironments. Tumor-derived extracellular vesicles are now recognized as carriers of key messengers secreted by primary tumors, signals that induce the formatio...

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Bibliographic Details
Main Authors: Alberto Hernández-Barranco, Laura Nogués, Héctor Peinado
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.625221/full