The Binary Toxin CDT of Clostridium difficile as a Tool for Intracellular Delivery of Bacterial Glucosyltransferase Domains

The Binary Toxin CDT of Clostridium difficile as a Tool for Intracellular Delivery of Bacterial Glucosyltransferase Domains

Binary toxins are produced by several pathogenic bacteria. Examples are the C2 toxin from Clostridium botulinum, the iota toxin from Clostridium perfringens, and the CDT from Clostridium difficile. All these binary toxins have ADP-ribosyltransferases (ADPRT) as their enzymatically active component t...

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Bibliographic Details
Main Authors: Lara-Antonia Beer, Helma Tatge, Carmen Schneider, Maximilian Ruschig, Michael Hust, Jessica Barton, Stefan Thiemann, Viola Fühner, Giulio Russo, Ralf Gerhard
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Toxins
Subjects:
binary toxins
Clostridium difficile
ADP-ribosyltransferase
glucosyltransferase
protein delivery
Online Access:http://www.mdpi.com/2072-6651/10/6/225

Internet

http://www.mdpi.com/2072-6651/10/6/225

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