Characterization of Mono- and Bi-Transgenic Pig-Derived Epidermal Keratinocytes Expressing Human <i>FUT2</i> and <i>GLA</i> Genes—In Vitro Studies

Characterization of Mono- and Bi-Transgenic Pig-Derived Epidermal Keratinocytes Expressing Human <i>FUT2</i> and <i>GLA</i> Genes—In Vitro Studies

Pig-to-human xenotransplantation seems to be the response to the contemporary shortage of tissue/organ donors. Unfortunately, the phylogenetic distance between pig and human implies hyperacute xenograft rejection. In this study, we tested the hypothesis that combining expression of human α1,2-fucosy...

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Bibliographic Details
Main Authors:	Jerzy Wiater, Marcin Samiec, Kamil Wartalski, Zdzisław Smorąg, Jacek Jura, Ryszard Słomski, Maria Skrzyszowska, Marek Romek
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Series:	International Journal of Molecular Sciences
Subjects:	genetically modified pig epidermal keratinocyte human α-1,2-fucosyltransferase human α-galactosidase A Galα1→3Gal epitope
Online Access:	https://www.mdpi.com/1422-0067/22/18/9683

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