Defects in DNA double‐strand break repair resensitize antibiotic‐resistant Escherichia coli to multiple bactericidal antibiotics

Defects in DNA double‐strand break repair resensitize antibiotic‐resistant Escherichia coli to multiple bactericidal antibiotics

Abstract Antibiotic resistance is becoming increasingly prevalent amongst bacterial pathogens and there is an urgent need to develop new types of antibiotics with novel modes of action. One promising strategy is to develop resistance‐breaker compounds, which inhibit resistance mechanisms and thus re...

Full description

Bibliographic Details
Main Authors: Sarah A. Revitt‐Mills, Elizabeth K. Wright, Madaline Vereker, Callum O'Flaherty, Fairley McPherson, Catherine Dawson, Antoine M. vanOijen, Andrew Robinson
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:MicrobiologyOpen
Subjects:
AMR
antimicrobial resistance
DNA repair
double‐strand break repair
resensitization
SOS response
Online Access:https://doi.org/10.1002/mbo3.1316

Internet

https://doi.org/10.1002/mbo3.1316

Similar Items