Defects in DNA double‐strand break repair resensitize antibiotic‐resistant Escherichia coli to multiple bactericidal antibiotics

Abstract Antibiotic resistance is becoming increasingly prevalent amongst bacterial pathogens and there is an urgent need to develop new types of antibiotics with novel modes of action. One promising strategy is to develop resistance‐breaker compounds, which inhibit resistance mechanisms and thus re...

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Hlavní autoři: Sarah A. Revitt‐Mills, Elizabeth K. Wright, Madaline Vereker, Callum O'Flaherty, Fairley McPherson, Catherine Dawson, Antoine M. vanOijen, Andrew Robinson
Médium: Článek
Jazyk:English
Vydáno: Wiley 2022-10-01
Edice:MicrobiologyOpen
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On-line přístup:https://doi.org/10.1002/mbo3.1316