Molecular understanding of unusual HbE-β+-thalassemia with Hb phenotype similar to HbE heterozygote: simple and rapid differentiation using HbE levels

Molecular understanding of unusual HbE-β+-thalassemia with Hb phenotype similar to HbE heterozygote: simple and rapid differentiation using HbE levels

AbstractBackground Low HbF expression in HbE-β+-thalassemia may lead to misdiagnosis of HbE heterozygosity. We aimed to characterize the β- and α-globin genes and the modifying factors related to HbF expression in patients with an Hb phenotype similar to that of HbE heterozygotes. Furthermore, scree...

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Bibliographic Details
Main Authors: Wittaya Jomoui, Surada Satthakarn, Sitthichai Panyasai
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Annals of Medicine
Subjects:
Hemoglobin E
Hemoglobin F
Heterozygous HbE
HbE-β+-thalassemia
Diseases
XmnI polymorphism
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2023.2267054

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https://www.tandfonline.com/doi/10.1080/07853890.2023.2267054

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