Role of Elevated Intracellular S-Adenosylhomocysteine in the Pathogenesis of Alcohol-Related Liver Disease

Role of Elevated Intracellular S-Adenosylhomocysteine in the Pathogenesis of Alcohol-Related Liver Disease

Background: The earliest manifestation of alcohol-related liver disease (ALD) is steatosis, characterized by the accumulation of lipid droplets (LDs) in hepatocytes. Findings from our laboratory have indicated that many pathological changes, including steatosis, correlate with the alcohol-induced he...

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Bibliographic Details
Main Authors: Madan Kumar Arumugam, Sharanappa Talawar, Laura Listenberger, Terrence M. Donohue, Natalia A. Osna, Kusum K. Kharbanda
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
hepatic steatosis
S-adenosylhomocysteine
alcohol
lipid droplets
lipases
perilipins
Online Access:https://www.mdpi.com/2073-4409/9/6/1526

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https://www.mdpi.com/2073-4409/9/6/1526

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