An enterococcal phage protein inhibits type IV restriction enzymes involved in antiphage defense

Abstract The prevalence of multidrug resistant (MDR) bacterial infections continues to rise as the development of antibiotics needed to combat these infections remains stagnant. MDR enterococci are a major contributor to this crisis. A potential therapeutic approach for combating MDR enterococci is...

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Bibliographic Details
Main Authors: Nathan P. Bullen, Cydney N. Johnson, Shelby E. Andersen, Garima Arya, Sonia R. Marotta, Yan-Jiun Lee, Peter R. Weigele, John C. Whitney, Breck A. Duerkop
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-51346-1