Cox proportional hazards regression in small studies of predictive biomarkers

Abstract Predictive biomarkers are essential for personalized medicine since they select the best treatment for a specific patient. However, of all biomarkers that are evaluated, only few are eventually used in clinical practice. Many promising biomarkers may be erroneously abandoned because they ar...

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Bibliographic Details
Main Authors: K. Jóźwiak, V. H. Nguyen, L. Sollfrank, S. C. Linn, M. Hauptmann
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-64573-9