Leucine-rich repeat protein PRAME: expression, potential functions and clinical implications for leukaemia

<p>Abstract</p> <p>PRAME/MAPE/OIP4 is a germinal tissue-specific gene that is also expressed at high levels in haematological malignancies and solid tumours. The physiological functions of PRAME in normal and tumour cells are unknown, although a role in the regulation of retinoic a...

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Bibliographic Details
Main Authors: Wadelin Frances, Fulton Joel, McEwan Paul A, Spriggs Keith A, Emsley Jonas, Heery David M
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/226