Leucine-rich repeat protein PRAME: expression, potential functions and clinical implications for leukaemia
<p>Abstract</p> <p>PRAME/MAPE/OIP4 is a germinal tissue-specific gene that is also expressed at high levels in haematological malignancies and solid tumours. The physiological functions of PRAME in normal and tumour cells are unknown, although a role in the regulation of retinoic a...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-08-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/9/1/226 |