The Ability of Zika virus Intravenous Immunoglobulin to Protect From or Enhance Zika Virus Disease

The Ability of Zika virus Intravenous Immunoglobulin to Protect From or Enhance Zika Virus Disease

The closely related flaviviruses, dengue and Zika, cause significant human disease throughout the world. While cross-reactive antibodies have been demonstrated to have the capacity to potentiate disease or mediate protection during flavivirus infection, the mechanisms responsible for this dichotomy...

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Bibliographic Details
Main Authors: Amelia K. Pinto, Mariah Hassert, Xiaobing Han, Douglas Barker, Trevor Carnelley, Emilie Branche, Tara L. Steffen, E. Taylor Stone, Elizabeth Geerling, Karla M. Viramontes, Cory Nykiforuk, Derek Toth, Sujan Shresta, Shantha Kodihalli, James D. Brien
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Zika virus
dengue virus
hyperimmunoglobulin
antibody dependent enhancement
animal model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.717425/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.717425/full

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