The interplay between the polar growth determinant DivIVA, the segregation protein ParA, and their novel interaction partner PapM controls the Mycobacterium smegmatis cell cycle by modulation of DivIVA subcellular distribution

The interplay between the polar growth determinant DivIVA, the segregation protein ParA, and their novel interaction partner PapM controls the Mycobacterium smegmatis cell cycle by modulation of DivIVA subcellular distribution

ABSTRACT Bacterial chromosome segregation is facilitated by the ParABS system. The ParB protein binds centromere-like parS sequences and forms nucleoprotein complexes. These nucleoprotein complexes are segregated by the dynamic ATPase ParA. In mycobacteria, ParA also interacts with the polar growth...

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Bibliographic Details
Main Authors: Izabela Matusiak, Agnieszka Strzałka, Patrycja Wadach, Martyna Gongerowska-Jac, Ewa Szwajczak, Aleksandra Szydłowska-Helbrych, Bernhard Kepplinger, Monika Pióro, Dagmara Jakimowicz
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
chromosome segregation
mycobacteria
polar growth
ParA
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01752-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01752-23

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